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| CMT PCMT DATA ITEM |
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MEANING: Compartment (CMT) and Prediction Compartment (PCMT) data
items for PREDPP
CONTEXT: $INPUT record and NONMEM data set
USAGE:
$INPUT ... CMT PCMT ...
DISCUSSION:
CMT and PCMT label PREDPP's compartment (CMT) and prediction compart-
ment (PCMT) data items. The compartment and prediction compartment
data items are optional. They may be used separately or together.
Their meanings depend on the particular kind of event record.
Observation Event:
CMT specifies the number of the observation compartment (the com-
partment whose scaled drug amount appears as F in the error rou-
tine). When this number is that of the output compartment, it is
allowed to have a negative sign, in which case the output com-
partment is turned off after F is obtained. By convention, the
number of the output compartment may also be given by the CMT
data item as the number 100 (this is true regardless of the type
of the event record). When CMT is 0, the default compartment for
observations is used.
PCMT is ignored.
Dose Event:
CMT specifies the number of the compartment into which the dose
is introduced. The dose compartment is turned on if it was pre-
viously off. When CMT is 0, the default compartment for doses
receives the dose.
PCMT specifies the number of the compartment for which an F value
is computed. When PCMT is 0, the default compartment for obser-
vations is used.
Other-Type Event:
A positive value of CMT specifies a compartment to be turned on.
A negative value of CMT specifies a compartment to be turned off.
When CMT is 0, no change is made in the status of any compart-
ment.
PCMT is the same as for dose events.
Reset Event:
CMT is ignored.
PCMT is the same as for dose events.
Reset-Dose Event:
CMT and PCMT are the same as for dose events.
REFERENCES: Guide VI Section V.H
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