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| EVID DATA ITEM |
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MEANING: Event Identification (EVID) data item for PREDPP
CONTEXT: $INPUT record and NONMEM data set
USAGE:
$INPUT ... EVID ...
DISCUSSION:
EVID labels PREDPP's event identification (EVID) data item. The event
identification data item is required. NM-TRAN can supply this data
item if dose and observation events are the only types of events
present in the data. EVID can have one of four values in any event
record.
0 Observation event. The DV data item is an observation. The CMT
data item specifies which compartment is being observed. Dose-
related data items (AMT, RATE, II, ADDL, SS) must be zero.
1 Dose event. The CMT data item specifies which compartment is
being dosed. The DV data item is ignored. One or more of AMT,
RATE, II, ADDL, SS data items must be non-zero to define the
dose.
2 Other-type event. The DV data item is ignored. Dose-related
data items must be zero. Examples of other-type events are: A
compartment is turned on or off (CMT specifies which compartment
is to be turned on or off); a prediction is obtained at a speci-
fied time so that it may be displayed in a table or scatterplot
(PCMT specifies the compartment from which the prediction is
obtained); a physiological variable changes.
3 Reset event. The kinetic system is re-initialized. Time is
reset to the time of the event record, the amounts in each com-
partment are reset to zero, the on/off status of each compartment
is reset to its initial status. The DV data item is ignored.
Dose-related data items must be zero.
4 Reset-and-dose event. The system is first reset, and then a dose
is given. The DV data item is ignored.
REFERENCES: Guide IV Section V.B
REFERENCES: Guide VI Section V.B
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