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| PRDPK3 |
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MEANING: PREDPP-PK common
CONTEXT: PK routine
USAGE:
COMMON /PRDPK3/ A_0,DA_0,D2A_0
DIMENSION A_0(PC),DA_0(PC,LVR),D2A_0(PC,LVR,LVR)
(If double precision is to be used):
DOUBLE PRECISION A_0,DA_0,D2A_0
(If single precision is to be used):
REAL A_0,DA_0,D2A_0
The values of PC and LVR must be the same as that found in file SIZES
(See sizes).
DISCUSSION:
PREDPP sets A_0FLG to 1 (in common PROCMC) at a call to PK with the
first event record of an individual record (if the data are population
data), with the first event record of the data set (if the data are
single-subject data), and with a reset record. At such times, the
amounts in the various compartments can be set by the PK routine. It
can do this by storing the initial values for the state vector and its
partials in common PRDPK3. The amount in the output compartment can
not be set.
A_0 A_0(n) = the amount for compartment n
DA_0
DA_0(n,i) = the derivative of A_0(n) wrt eta(i)
D2A_0
D2A_0(n,i,j) = the second derivative of A_0(n) wrt eta(i), eta(j)
(lower-triangular; j=1, ..., i)
There is a one-to-one correspondence between elements of common PRDPK3
and those of common PROCM4.
NM-TRAN includes common PRDPK3 in the PK routine when the $PK block
includes references to variables A_0FLG, A_0, or A_INITIAL, or when
verbatim code is present.
(See procmc, procm4).
REFERENCES: None.
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