___________________________________________________________________
 |                                                                 |
 |                         DEFAULT COMPARTMENT                     |
 |_________________________________________________________________|

 MEANING: Default compartments for kinetic models with PREDPP
 CONTEXT: NONMEM data set

 DISCUSSION:

  The prediction computed by PREDPP is a scaled  drug  amount  in  some
 compartment  called  the observation compartment.  Every dose is input
 into some dose compartment.

 With every kinetic model there are designated  a  default  observation
 compartment  and  a default dose compartment. For some kinetic models,
 these designations are built into the model  definition;  for  others,
 these  designations are given by the user in the user subroutine MODEL
 (or in $MODEL abbreviated code).

 Unless otherwise specified on an observation event record by means  of
 the  compartment data item (CMT), the observation compartment is taken
 to be the default observation compartment. Unless otherwise  specified
 on a dose event record by means of the compartment data item, the dose
 compartment is taken to be the default dose compartment.

 The models for which default  designations  are  built-in  are  listed
 here.  The numbers are the compartment numbers.

 Model     Default dose compartment   Default observation compartment

 ADVAN1               1                              1
 ADVAN2               1                              2
 ADVAN3               1                              1
 ADVAN4               1                              2
 ADVAN10              1                              1
 ADVAN11              1                              1
 ADVAN12              1                              2

 (See cmt, $model, model).

REFERENCES: Guide VI Section V.H, VI.B, VII.C
REFERENCES: Guide IV Section V.C.4


  
Go to main index.
  
Created by nmhelp2html v. 1.0 written by Niclas Jonsson (Modified by AJB 5/2006,11/2007)