___________________________________________________________________
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 |                                TRANS3                           |
 |_________________________________________________________________|

 MEANING: Choice of Translator Routine for PREDPP
 CONTEXT: Option of NM-TRAN $SUBROUTINES record

 USAGE:
 $SUBROUTINES [TRANS=]TRANS3

 SAMPLE:
 $SUBROUTINE ADVAN3 TRANS3

 DISCUSSION:
 TRANS3 is a routine in PREDPP's library which can be used with  ADVAN3
 or  ADVAN4.   It performs a reparameterization of the basic PK parame-
 ters to the internal parameters K, K12, K21, and KA.

 Basic PK parameters for ADVAN3, TRANS3:

   CL    clearance
   V     central volume
   Q     intercompartmental clearance
   VSS   volume of distribution at steady-state

   Relationship:
   K=CL/V
   K12=Q/V
   K21=Q/(VSS-V)

 Basic PK parameters for ADVAN4, TRANS3:

   CL    clearance
   V     central volume
   Q     intercompartmental clearance
   VSS   volume of distribution at steady-state
   KA    absorption rate constant

   Relationship:
   K=CL/V
   K23=Q/V
   K32=Q/(VSS-V)
   KA=KA

REFERENCES: Guide VI Section III.A, VII.C.3


  
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